If you are a technologist/generalist, aiming for small companies is a good strategy. If you're not in SV even better, you may end up in a real grass roots business and a really interesting problem domain that is ostensibly Not Software.

I personally, cannot stand the software for software industry. You, me, we have all built such arbitrary bullshit machines that link together in a web of unnecessary business. We lambast redundant jobs and useless management, but a moment of reflection for our industry and just how much software we have built for entirely self-serving purposes. So many man hours spent on the ephemeral whims of software. Sorry for the cynicism.

Less cynically, I feel the smaller the company, self-funded, the more likely a generalist will thrive and the business domain will be real-world and impactful. If it's venture funded and can pivot to advertising, it probably will. If you move away from tech hubs the wages are lower, but you might find a more fulfilling role.