Nobody is going to pay human rates to do the stuff that AI can do for much cheaper either! The quip about jobs being vestigial was also a tongue-in-cheek indication that Economics as we know now also will not apply.

This leaves only one area for humans to expand into: towards the things machines cannot do, which often involve things that neither humans or machines currently understand.

Fortunately, that's basically everything. We know about black holes, but we still don't know enough to figure out FTL travel. We know DNA but we don't know enough to cure cancer, let alone how to reverse aging. We know a negligible fraction of the secrets of the universe, and it would be a much better use of human intellect to figure those out than filling out TPS reports.

Unfortunately, current society is not set up for that future -- essentially where everybody is either a scientist or an artist, both historically terribly-paying jobs requiring a very specific mindset and an appetite for abject uncertainty -- and that's where the upheaval happens.