Also, the liver metabolizes a lot of toxins, and some cells die in the process, so there was a strong pressure to replace them. That pressure was our ancestors insisting on eating toxic things like mushrooms and spoiled food until it didn't immediately kill them.
> our ancestors insisting on eating toxic things like mushrooms and spoiled food
Presumably this didn't happen because are ancestors were dumb, but rather because the ability to process slightly spoiled food is a significant advantage in an environment where fresh food is sometimes scarce?