Like everything, depends on the usecase. An email desktop app seems to be a valid one. A standard earlystage B2B SaaS Rails web app? Not so much.

Same with server side rust. A high volume transactional backend email service makes sense there. The base layer of a CRM managing a lot of business logic?

Life will go on much the same. We just have more options to say yes to 'native' with LLMs, we can experiment more with ideal scenarios rather than a religious adherence to cross platform or single-framework merely for team DX simplicity.