Yes the EPA should be able to regulate noise pollution too, unless maybe if another agency is doing that job.
No, there is no issue to have that definition encompassing all of what in society causes damage to the open environment[1].
Note that your wording, "encompasses [...] all of society", does not correspond to my stance. It only encompasses what causes negative externalities in the way I defined.
It is crucial that there exist such an agency (EPA) that examines these environmental negative externalities (let's just call it pollution now, as it is so defined), and considers ways to limit it.
Each agency has its own axis, and it is the combination of them that is effective: if you only leave the energy sector to e.g. the USEA (US Energy Association), they won't have the incentive, definition, or analysis axis in the direction of looking at human health or forests decline, purely because it is not in their definition or their statuses.
Similarly, if you are left with just the EPA, they won't provide the expertise to evaluate if this or that type of electricity generation is feasible and with which kind of technology.
It just the division of expertise, the division of labor, and that's why scientists and engineers work together across domains!
[1]: damage should be defined relative to a severely detrimental impact to the biosphere or to human society. The environment is understood to be open as defined by not having clear boundaries that may, for example, keep the impact strictly contained within the limits of a volume property of the agent of this impact. Air is typically not contained in such a delimited volume, and is thus open environment. Water also flows freely and is connected to e.g. big bodies of water. And so on.
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About "modules":
"Software people should be able to understand the importance of separation of modules."
The "energy" module cares about the watt-hours produced but doesn't care about the cancer caused by the smoke!! (or, for CO2, about the planet-scale extinction event caused by raising temperatures, or the multiplying forest fires)
Thus you need the "pollution assessment and mitigation" module!
There. Proved to you that I am a SE :))