Don't live for the weekend. Why 2 out of 7 days when you have another 5. Don't put off til the weekend. Don't put off til annual vacation. Don't put off til retirement. Live life every day.
As for each day, organize around living your life. For me, that means working a schedule from the other coast so I sleep when my body craves it, and not fighting it to be productive when I simply am running on reserves