Safari doesn't run on Windows or Linux. WebKit does run outside of Apple's environment but no major browser uses it which means you are left Firefox, a Blink based browser or a WebKit browser that 5 people use.

Safari runs on many, many millions of various Apple devices though, and I think that more than qualifies it as a major/mainstream browser, and the same for Webkit as a mainstream engine... especially considering Safari's market share is ~5x higher than Firefox. You may disagree though, and that's ok.