How many bureaucracies in history have behaved in deeply misanthropic ways, especially when led by misanthropic leaders?

Don't underestimate the power of the desire to keep one's job to cause a large organization to behave towards its own self-perpetuation despite the moral lines that must be crossed by individuals to do so.

> How many bureaucracies in history have behaved in deeply misanthropic ways, especially when led by misanthropic leaders?

Lots!

> Don't underestimate the power of the desire to keep one's job to cause a large organization to behave towards its own self-perpetuation despite the moral lines that must be crossed by individuals to do so.

I don't. I don't put anything past people.

Yes, lots, look at the current US government.