Some climate models expect permafrost decay and/or mere GHG rise to erode the ozone layer. It’s not 1:1 proven, but there’s indication that in a post-4C world (with feedback loops), we might slowly lose our protection against the sun’s radiation.

I don’t recommend getting into the literature, it’s… depressing.

(Your point about the global, concerted effort to limit the “holes” in the ozone layer reminds me that we can, when pressed, come together to tackle serious issues.)