Asking out of curiousity - how would you or how does your org handles this right now?

I'm not the previous poster, but in my experience you can get a lot of mileage out of having dev teams (tediously, at least the first time) go through all potential vulnerabilities, decide how risky each one is based on likelihood and impact, and then get them to address the high/highs somehow (e.g. by upgrading a dependency, or writing extra code to guard against the issue, or fixing the issue if it's a home-grown vulnerability).