Not for me, I always turn off animations. It feels fine for me, and I can operate the phone a lot quicker without having to wait for animations to complete.

I don't turn them off entirely, I kind of enjoy the feeling of momentum animated elements can provide, but I definitely do go in and speed them up massively. I find that when a phone is feeling unresponsive or sluggish, it's usually because I'm moving two steps ahead of the animation and it has to catch up. Feels like tripping on your own feet.