I attended a talk by Brian at Stanford, and I asked why not just use Gibson assembly to stitch together 5 kb synthesized strands from a company like Twist Biosciences.

The answer I got was along the lines that they were simply going to get around to do the actual lab work at some point.

DNA synthesis technology hasn't really been a blocker for generative bio projects except at the full chromosome level.

And I think simply generating a full chromosome and booting it up without doing due diligence is probably a recipe for disaster.

We honestly aren't that far away from AI slop enzymes, AI slop ligases, and eventually AI slop bio weapons...