You could try https://github.com/dscharrer/innoextract (installable via homebrew).

I wondered if innoextract was Linux only, but I see there is a homebrew formula. https://formulae.brew.sh/formula/innoextract

Is the author reading hackernews?

That, or just run it with wine.

Interestingly, wine works on Apple Silicon via Rosetta2 so I guess it won't work by macOS 28, and we will be only left with arm64 DOSBox-X.

... and arm64 innoextract hopefully