It's close enough that DBOS does support SQLite. [0] The default for prototyping is SQLite, but sure you can run it in production if you wanted.
Obligatory list of workflow engines and libraries because it's such a common need that a lot have rolled their own. [1]
[0] https://docs.dbos.dev/python/tutorials/database-connection
What would be the main differences between DBOS and Obelisk?
Hi, I wrote a comparison blog post between Obelisk and the Java version of DBOS a couple of months ago: https://obeli.sk/blog/comparing-dbos-part-1/