I am, I have an Nvidia 5070 Ti, Aurora for my OS (from the same people as bazzite, but I'm a light gamer so I'm fine using flatpak steam/heroic/etc). the only problems I've faced are

- occasionally an online game breaks and it's usually fixed within a day or two. for example at some point a Battle.net update broke the launcher under Wine some time last year, then for a while Overwatch would intermittently crash once every few sessions. I haven't gamed on Windows in years so I can't even compare anecdotally, but I suspect Windows is probably slightly more stable with live service games. I've never had any issues with a single player game, period. (YMMV)

- DX12 performance is 10-20% worse on Nvidia. This should be improved Soon (TM) - I think the last piece is https://github.com/HansKristian-Work/vkd3d-proton/tree/descr...

- Some anticheats block Linux - the only times I've switched over to windows in the last year have been when some friends wanted me to play Marathon with them

- Running 'sidecars' alongside your games or modding works but is generally more of a hassle with wine

things I didn't expect to work but do:

- Game streaming with Sunlight works fine to Samsung TV via the TizenOS Moonlight app

- Nvidia had suspend issues for a year but those have all been sorted out the last few months