For building web applications or a system that includes logic that needs to run on the web? TypeScript is mature enough, and it's top tier for domain modeling. As long as you stay disciplined, Claude Code will write excellent TypeScript for you, and you can run it pretty much anywhere.

The only reasons to hesitate, imo, are (A) you're worried that it won't perform as well as you need on your servers, or (B) you're scared of npm supply chain attacks.