As mentioned, "podman/docker run -it $my-image codex" also actually has the requisite isolation by default, no need for special software. Biggest risk is accidental deletion of stuff, easily solved without running an entire VM, which "smol" machines seems to be. No doubt VMs have their uses too, but for simple isolation like this I personally rather use already existing tooling.
As mentioned, "podman/docker run -it $my-image codex" also actually has the requisite isolation by default, no need for special software. Biggest risk is accidental deletion of stuff, easily solved without running an entire VM, which "smol" machines seems to be. No doubt VMs have their uses too, but for simple isolation like this I personally rather use already existing tooling.