Really? I get headaches semi-frequently and my first line of defense is ibuprofen, I use acetaminophen sporadically as a last resort

Why? Does ibuprofen work better? It's bad for your stomach walls.

There seems to be some percentage of people that acetaminophen seems to do very little for. Ibuprofen has a much more pronounced effect, to the point that I take it at half it's recommended dosage.

> Does ibuprofen work better?

In my experience it works far better at managing headaches/migraines.

I take both. 500-1000mg acetaminophen, 200-400mg ibuprofen. Usually helps for headaches which I get frequently. I only take them for the worst headaches though, so probably once every couple of weeks on average.

Yeah if I need to I take both also. In addition I be sure to have a caffeinated drink also as caffeine has been shown to both speed the absorption and boost the efficacy (5-10%) of paracetemol over a multi hour period. https://pubmed.ncbi.nlm.nih.gov/17442681/