I am working on bUniProbe (https://www.crowdsupply.com/bitmerse/buniprobe), an open-source wireless hardware debugger. I was tired of juggling separate USB adapters for SPI, I2C, UART, CAN and GPIO and wiring up external level shifters just to switch between 3.3V and 5V targets.
To fix this, I built a single Wi-Fi connected board that handles it all. It hosts its own web server, so you can monitor signals, read/write data, and toggle hardware pull-ups directly from your browser without installing drivers. I also added a waveform viewer and a REST API for all interfaces, making it easy to automate hardware testing with Python scripts.
Hardware and firmware will be fully open-source. We are currently in pre-launch on Crowd Supply.