Thank you, I am somewhat aware of the knobs present on a synth, though fail to see the relevance given that various other instruments do not have dynamic retuning options. Which 12 tone scale did you have in mind (for there are many) and why do you think 12 (for there are many other numbers, some of which are used by various scale systems) is a natural property of the world? Perhaps with a more cogent argument you could make a better case for your opinion.