For Swyer syndrome, A 2017 study estimated that the incidence of Swyer syndrome is approximately 1 in 100,000 females. Fewer than 100 cases have been reported as of 2018.

For both the genetic disorders, they would have to be beneficial or at least not an disadvantage, for elite sport activity in order to be an issue for misclassification. For a sex-determination system, they could simply add an exception for Swyer syndrome and postpone the decision until such individual presented themselves at an Olympic competition.