Startup time does not matter, use the daemon. Opening a new frame is ~instantaneous.

I practically live in Emacs and it's not slow at all. It's very zippy, and my setup isn't the lightest!

There's a new branch (feature/igc) with incremental garbage collection (via MPS) that makes routine actions faster. I've been using it and it has been incredibly stable and has completely eliminated stutters (which used to happen very infrequently, but were present). Also, to me, it seems like it improves latency. The cursor feels more responsive.