I live remotely in a very isolated area and work remotely (no slack, just email). I live with my partner but she is in town for work during the day. I go to town a couple of times a month. Before COVID I had an office in town but realized I don't need it. I've lived here for about 15 years.
Initially I was lonely occasionally during the day but it went away. I'm now perfectly comfortable with no human contact except comments (like this) on the internet for very long stretches. My girlfriend went on a 3 week trip to visit family last year and I visited town twice and saw a friend once during that time and had one long phone conversation with a brother. It was a perfectly comfortable 3 weeks. I don't play video games.
I'm not recommending this way of life. It's probably more psychologically healthy to have people around and so I have to recommend trying to rebuild social connections as you can, but the point is for your situation, it gets much more comfortable as time passes. I don't want to say "it's all in your head" but something along the lines of that sentiment is kind of how it works I think. You do need something to do, a reason to get up in the morning. I garden and keep animals.