I did it today. It took me thirty minutes to fix the networking because I couldn't get Little Snitch to uninstall since it didn't seem to be compatible. Basically I had to reboot in recovery mode to disable security features (csr) to uninstall Little Snitch (via systemextensionsctl). This is the worst update I've ever gone through on Mac, and I started using a Macintosh SE.
It's a bit unfair to complain about your OS being broken by incompatible software that modifies the kernel.
In the past, MacOS has automatically made a folder of incompatible software that it leaves on the desktop. Little Snitch seems like something that could have been tested.
It is a commonly used extension, which was restricted so that I could no longe remove it. What's more odd is that supposedly I was running the latest version.