>long-term societal importance without bringing in any form of centralized resource allocation.
The onus is on the biomedicine industry to demonstrate it's capable of producing anything of societal importance because so far it's largely failed to deliver. There's nothing noble or scientific about throwing good money after bad into an industry that's continuously failed to deliver.
More people living more after cancer diagnosis? (ref: https://www.cancer.org/research/acs-research-news/people-are...)
You'll note I didn't try to specify what was of import.
We can create mechanisms that enable more people to follow their own idea of what is important instead of merely what is lucrative. Not everyone will agree with the choices other people make, and it wouldn't eliminate money as a motivating factor, it would just slightly reduce the strength of that signal relative to other potential signals such as "I feel like I'm doing something meaningful."
Honestly I think you'd be better off just making _existing_ cheaper than trying to discourage wealth seeking. The cost of living, especially housing, is a huge motivating factor to try and 'get rich first', before doing the 'meaningful work' part.
Antibiotics? Vaccines?