What's the target?

If you're deploying applications to desktop/laptop, Microsoft stack seems like the biggest market share by a lot.

Anything else, probably not. Microsoft may have advantages in servers, or at least they have had some in the past: my go to example is Receive Side Scaling [1] was originated at Microsoft and is amazing in some use cases. But those advantages most likely aren't big enough to justify the hassle of wrangling and paying for licenses. Running your servers on open source software makes everything easier.

[1] https://learn.microsoft.com/en-us/windows-hardware/drivers/n...