I am an S-exp enjoyer, and more for practical reasons than aesthetic ones—I really like the editor tooling that's possible with S-expressions. So I will absolutely choose a Lisp or a lisp if given the option, even at some level of inconvenience when it comes to the maturity of the language itself. I will always write Hy[0] rather than Python, for example.
(I am aware of Combobulate[1] for Emacs folks, of which I'm sadly not one.)
The most machine-friendly syntax - and the least appropriate for our LLM overlords which get confused by parenthesis because they don’t see the structure.
Have you tried? LLMs are really good at elisp, which is strange because elisp code is almost always GPL.
There's an option beyond lisp. Forth has even less syntax.
In my experience, they find counting parenthesis as difficult as counting the r's in strawberry if it was spelled srtrawrrrbrrerryrrrr.