> The cells in your eyes have exactly the same DNA as the cells in your big toe

Is that true?

I know that cells in the brain have significant variability in DNA, but not really aware of what non-neuronal and non-brain cells in general typically have.

Every cell in your body (excepting red blood cells) has a complete copy of your genome. What differs is which portions are activated.

Except for in the brain (13% to 41% of neurons with variation, deletions, additions, etc., first discovered in 2001, study below from 2013 confirmed).

https://www.science.org/doi/10.1126/science.1243472