Running NixOS based Nextcloud for everything. Multiple family members getting their including me getting their Photos and Videos auto-uploaded and handled by NextCloud's Memories [1].
Awesome experience, but you really have to stick to the happy path. Even with a super powerful CPU, Videoplayback was unusable, until a dedicated AMD GPU handled the transcodes. Even though it's Fiber To the home, sometimes Upload speeds collapse for no apparent reason and it's unusable.
All in all impressive such a massive FOSS project runs at all.