A change in mindset must happen, but the proper mindset in which to change one's mindset is elusive. Even if my mindset today is flawed, what specifically should stay and what should go to make myself a better person? It feels like leaping from a safe harbor into the unknown. Can you convince a person to kill themselves and let a near-copy-but-not-quite live their life instead?
That being said, I think some positive change can be produced with diligence and care, even if the methods and details are hazy even to the person enacting them.