Completely orthogonal to the feeling of small/unimportant, my mind gets rolled up in thinking about how much activity is going on that's not being experienced by anyone. Think of the raging storms on venus' surface or the ice volcanoes on Io, or the methane raining down on Titan..all that stuff is happening right now, as we speak. But nobody is there to feel it or hear it or see it. And that's our own solar system. Imagine how many things are happening galaxy wide or beyond. So much stuff is happening right now!! This boggles my mind because it doesn't rely on any speculation about alien life. It's almost certainly a fact, unless we're in a simulation and the rest of the universe is in the "clipping plane" of the scene.