I have an HDHomeRun box and use it through Plex. I've never installed the HDHomeRun software. Plex immediately recognized it as soon as I plugged it in. There is a noticeable amount of latency between selecting a channel and starting the stream, so channel surfing is pretty cumbersome, but I almost never do that. With the paid version of Plex (Plex Pass), you also get DVR support which automatically removes commercials from the recording, so that's pretty much the only way I use it.