GCC's sanitizer does not catch unsigned wraparound. But the bigger problem is that a lot of code is written where it assumes that unsigned wraps around and this is ok. So you you would use a sanitizer you get a lot of false positives. For signed overflow, one can always consider this a bug in portable C.

Of course, if you consistently treat unsigned wraparound as a bug in your code, you can also use a sanitizer to screen for it. But in general I find it more practical to use signed integers for everything except for modular arithmetic where I use unsigned (and where wraparound is then expected and not a bug)