Could you elaborate on "orientation"?

Let's say for C-to-C, are you talking about swapping the head/tail? Or simply connecting at a different angle (180 degrees)?

Probably 180 degrees rotation in the plug (on either end). It commonly happens if one of the contacts or conductors for USB-PD signalling is not working correctly. (because of the way the pinout is designed to work either way around, the conductors that are used for signalling swap roles depending on the orientation)

Yep, 180 degree rotation.

Yeah so probably one or more of the pins are bad in your cable, since the usb c pin design the same from left to right in either orientation: https://www.delock.com/infothek/USB-3.2_USB-Type-C/usb-3.2-u...

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