My expectation, they will perform great! I’m now mostly benchmarking on 192 core Intel, AMD, and Arm instances on AWS, and in some workloads they come surprisingly close to GPUs even on GPU-friendly workloads, once you get the SIMD and NUMA pinning parts right.
For BioInformatics specifically, I’ve just finished benchmarking Intel SPR 16-core UMA slices against Nvidia H100, and will try to extend them soon: https://github.com/ashvardanian/StringWa.rs