I think if you're looking from a normal couch to TV distance, you probably can't tell the difference.

If you're sitting computer desk to monitor distance (close enough to read text), you probably can tell a difference. From there, I think there is some false nostalgia at worst or subjectivity at best. Did computer monitors even have (noticeable) scanlines? I don't remember them while playing Wolfenstein or playing around in MS paint on windows 3.1... Maybe playing gorillas in DOS, but I can't remember...

If you're emulating snes on a modern PC, people like to say "games were developed with scanlines in mind", but they were also developed assuming you'd have a small TV and would be sitting ~8ft away from it!