There is a joy and psychological benefit to having minor, positive social interactions. If you are mostly seeing your partner and coworkers, or even working from home, you may not realize how little human interaction you have.
This is not to say that every McDonald's employee is a joy to be around. But it is good for your brain to smile at a stranger face to face and make a little small talk every now and then. It is also a skill you have to practice or it becomes hard to do.
This seems like simply a personal preference, which will be different from person to person. I WFH now, and I can go (and have gone) months without seeing another human being besides my family. I don't feel like this has been "bad" for my brain or for my personal joy or psychological wellbeing.
Eh, I hang out with people on the weekends. While shopping I want my headphones in to block all the horrible advertising they play on the speakers.