Acetaminophen related deaths are a few hundred a year in the US.

Opiate related deaths in the US have been around 50,000+/yr.

I don't personally know anyone who has died from acetaminophen usage or even particularly injured. I personally know several people who had their lives nearly destroyed by opiate abuse, and a few others who have died. And it's not like I'm hanging out with junkies all the time.