So in summary: taking 4x the recommended dose of a medication is dangerous?

How many other medications would that apply to? Countless, I imagine. That’s why we have dosages on every bottle.

paracetamol is unusual in this respect, that the toxic dose is so close to the therapeutic dose, but the benefits outweigh the risks.

after I had dental surgery, I took paracetamol and ibuprofen in alternate doses every 4h - I would have been in screaming pain if I couldn't have both as an option.

Maybe by FDA-type standards, 4x is "close", but to me, I would think it absurd to take 4x the recommended dose of something unless directed to by a doctor.

I was recently prescribed 800mg ibuprofen for an injury, where 200mg is the standard OTC dose, and I even questioned that.

you'd be surprised how casual some people are with doses. my old grandma had a big bag of medication she had collected over the years and occasionally she'd sit down and pick a couple like smarties and gulp them down.

when my dad decided to step in, he took her to a doctor to get a full review and confiscate the bag.