Which is what? Lots of this admin's actions have made sense once you know the underlying agenda—thanks project 2025 for spelling a lot of it out—but this one has me baffled. Taking on the woke… tylenol industry?
Which is what? Lots of this admin's actions have made sense once you know the underlying agenda—thanks project 2025 for spelling a lot of it out—but this one has me baffled. Taking on the woke… tylenol industry?
It’s simple, RFKj is a well-intentioned idiot.
Looking around for sources from before the world ended I can find quite a few reputable studies that show the correlation. The effect size is small ~0.4% in absolute risk but statistically detectable. Like okay, sure. Doctors already tell pregnant women to limit NSAIDs. So… we keep doing that. Mission accomplished?
The advice to avoid NSAIDs in pregnancy (and contraindication in the third trimester) doesn’t cover acetaminophen, though, because it’s not regarded as an NSAID (different mechanism of action and minimal anti-inflammatory effects.)
From a recent meta analysis, a total of 6 studies meeting the inclusion criteria addressed the association between acetaminophen exposure in utero and ASD. The odds ratio for the aggregated data was 1.19 which puts the 0.2-0.4% relative risk increase depending on what baseline incidence you assume (along the lines of your estimate.)
If you take the baseline incidence to be 1% then I calculate the NNH - number needed to harm, at 533, meaning you have to expose 533 pregnant women to acetaminophen to observe one additional case of ASD.
Given that the current public health administration of this era in the U.S. operates by seat-of-the-pants guidance rather than statistical evidence, the statistics are irrelevant to them. My advice would be that health care providers caring for pregnant women have an informed discussion about the risk and call it a day.