> absurdities like having the default queue be thread safe (sacrificing performance).

Why is this absurd? What are you writing where you need to scrape this sort of performance, but are perfectly fine with the overhead of interpreting bytecode at runtime, heap-allocating objects to represent floating-point numbers, not having homogeneous-type arrays that can store their elements contiguously in memory but which must indirect them, etc. etc. etc.?

Alternately, what world are you living in where everything a program does is CPU-bound and must be done efficiently? In this world, what led you to examine or try Python in the first place?