Thanks for the question! I just checked out pg-boss. Solid library if you're fully on Postgres. Sidequest.js takes a broader and more flexible approach. Key differences:

Database agnostic: Sidequest isn't tied to Postgres. It also works with MySQL, MongoDB, and SQLite, which helps if your stack isn’t Postgres-based.

Job isolation: Jobs run in worker threads, so heavy tasks won’t block your main Node.js process. Express APIs stay responsive.

Distributed coordination: Designed to run across multiple instances. One node picks up the job, and if it fails, another can retry. This is built-in.

Built-in dashboard: Includes a web UI to inspect, retry, or cancel jobs.

More than queues: Supports cron jobs, uniqueness constraints, per-queue concurrency, and configuration. Some of this overlaps with pg-boss, but the intent behind Sidequest is to provide a complete solution for job processing.

If you just need simple queues in a Postgres-only setup, pg-boss is great. If you want more flexibility, tooling, and backend options, Sidequest may be a better fit.