LA has a project where sterile male mosquitos are released[1]. Females only mate once, so this absolutely wrecks mosquito populations. It's the same strategy that keep screwworms contained at the Darrien Gap.
[1] https://www.glamosquito.org/2024-04-12-innovative-pilot-prog...
Screwworms have actually broken through the Darrien Gap and hopes of recontaining them are slim.
https://www.theatlantic.com/science/archive/2025/05/screwwor...
I'd say the USDA will handle this, but there has never been less competent leadership at the top so we're probably toast unless someone is brave enough to let rip with a gene drive attack (which I would personally love to see, biotech reactionaries be damned).
This is by far the safer way to do these things. You never know what's going to happen when you Geneer a completely new organism and then release it into the wild.