It is also interesting to consider, that if all transcendental numbers exist physically, then it basically means that there is an experiment that yields the Nth digit of such a number (for any N assuming unlimited physical resources to realize the experiment). If such experiment does NOT exist though, then there cannot be any relevance physically of that Nth digit (otherwise the "relevance" would materialize as an observable physical effect - an experiment!). This is something Turing machines cannot do for uncomputable numbers, like Chaitin's Omega, etc. We can yield the Nth digit of _many_ transcendental numbers (PI, e, trig functions, etc), but not all of them. It is so interesting that physics, machines and the existence of all the real numbers are so intertwined!
Of course one can also ponder, even if a mathematical object is "un-physical", can it be still useful? Like negative frequencies in fourier analysis, non-real solutions to differential equations, etc. Under what conditions can "un-physical" numbers be still useful? How does this relate to physical observation?
And just for the fun of it: when you execute unit tests, you are actually performing physical experiments, trying to falsify your "theory" (program) :D