We use mattn's go-sqlite3 in our SaaS product. It's not ideal from a toolchain perspective (i.e. cross compiling becomes a little annoying, especially with multi-arch Docker images) but once you get across that hurdle, we haven't run into any major problems with cgo.

The problem with cgo is it reduces portability, not that it causes issues. If whatever C you’re invoking doesn’t build on your architecture or if you need to cross-compile (last I checked), you’re out of luck.

I bet SQLite3 builds on more platforms than Go.

It’s not about the build platform, it’s about the execution platform and not having to have a toolchain for every platform. This is especially relevant in the embedded space.