Obviously not.
Even if you dislike the REX prefixes of AMD64, you've got to think about the 66/F2/F3 prefixes used for older SIMD instructions. They were introduced by Intel and basically contribute to more opcode bits. There's also the 2E/3E prefixes used for static branch prediction hints in some Pentium 4's (and also in new/upcoming Intel CPUs). VEX is from Intel, EVEX is from Intel, and the upcoming REX2 is also from Intel.