Does uv use a sandbox or do process isolation?

I've switched to running any and all python projects in Docker as a way to ensure that low effort supply chain attacks doesn't easily get everything in my home dir. So even if I use uv, I'd only do that in a Docker image for now

No idea. Probably not?

Docker images are a productivity killer. I don’t want to waste even 1 second building an image. And all the hoops you have to jump through to enable rapid iteration aren’t worth it.

Docker Images are fine - I guess - for deployment. But for development I absolutely hate them.