I agree that having a reliable main environment for quick experiments is great! On Windows I just use the main Python installation as a global environment, since no system stuff depends on it, on Linux I tend to create a "main" environment in the home directory. Then I can still have per-project environments as needed (say with uv), for example for stuff that I need to deploy to the VPS.

Note that I'm mostly in the research/hobby environments - I think this approach (and Python in general, re: some other discussions here about the language) works really well, especially for the latter, but the closer you get to "serious" work, the more sense the project environment approach makes of course